Search Result

Search Results for " apoptosis inhibitor 5 "

Targets

110

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T1349	5-Fluorouridine		Others , DNA/RNA Synthesis
	5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...		Others , DNA/RNA Synthesis
T0984	5-Fluorouracil	5-FU,Fluorouracil,NSC 19893,5-Fluoracil	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , DNA/RNA Synthesis , Endogenous Metabolite
	5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis ...
T8138	Phenazine methylsulfate	Phenazine methosulfate	Apoptosis , Antibacterial , Antibiotic
	Phenazine methylsulfate is anti-bacterial agents.		Apoptosis , Antibacterial , Antibiotic
T23450	TCS PrP Inhibitor 13	5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One	Others
	TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.		Others
T16087	Quiflapon	MK-591	Apoptosis , FLAP
	Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr...		Apoptosis , FLAP
T6371	AGK2		Apoptosis , Sirtuin
	AGK2（IC50=3.5 μM） is an effective, and specific SIRT2 inhibitor.		Apoptosis , Sirtuin
T8742	G5-7	JAK2 inhibitor G5-7	Apoptosis , JAK
	JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for g...		Apoptosis , JAK
T0365	Thioridazine hydrochloride	Mellaril,Aldazine	Apoptosis , Potassium Channel , Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Autophagy
	Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
T11571	HLY78	4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine	Wnt/beta-catenin
	HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.		Wnt/beta-catenin
T2258	VER-50589	VER50589	Apoptosis , HSP
	VER-50589 is a potent HSP90 inhibitor.		Apoptosis , HSP
T6916	OICR-9429	OICR 9429	Histone Methyltransferase , JAK
	OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.		Histone Methyltransferase , JAK
T6611	NSC697923	2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct me...		E1/E2/E3 Enzyme
T0964	Floxuridine	5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640	Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
	Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T6893	MK-886	MK886,L 663536	Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
	MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.		Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
T6525	GW 5074	GW5074,Raf1 Kinase Inhibitor I	Apoptosis , Raf
	GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.		Apoptosis , Raf
T1090	Perphenazine	Perphenazin,Etaperazine,Trilafon	CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T1567	Olanzapine	LY170053	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR
	Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T4263	BAY 61-3606	Syk inhibitor IV	Apoptosis , Syk
	BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.		Apoptosis , Syk
T22051	BU 224 hydrochloride		Imidazoline Receptor
	BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.		Imidazoline Receptor
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T8445	PU02	PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine	Apoptosis , 5-HT Receptor
	PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.		Apoptosis , 5-HT Receptor
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T9373	DCH36_06	(5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	Apoptosis , Epigenetic Reader Domain , Histone Acetyltransferase
	DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) as a bona fide is a potent p300/CBP inhibitor
T16079	Mirodenafil	SK3530	PDE
	Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T3602	D-Pantothenic acid sodium	D-Pantothenate Sodium,D-Pantothenic acid sodium salt,Sodium pantothenate,vitamin B5 sodium	Apoptosis , Others
	D-Pantothenic acid sodium (vitamin B5 sodium) , the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and ...		Apoptosis , Others
T4215	TCS-PIM-1-4a	SMI-4a	Apoptosis , Pim
	TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM).		Apoptosis , Pim
T8934	(6R)-FR054	FR054	Apoptosis , Others
	(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.		Apoptosis , Others
T6498	Fenoprofen calcium hydrate	Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate	Apoptosis , Others , COX
	Fenoprofen calcium hydrate (Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).		Apoptosis , Others , COX
T6173	BI 2536		Apoptosis , Epigenetic Reader Domain , PLK
	BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.		Apoptosis , Epigenetic Reader Domain , PLK
T8825	Capmatinib 2HCl.H2O	INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O	c-Met/HGFR
	Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.		c-Met/HGFR
T8416	Capmatinib xHCl	INCB28060,Capmatinib hydrochloride(free base),INC280	c-Met/HGFR
	Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activit...		c-Met/HGFR
T1963	Capmatinib	NVP-INC280,INC-280,INCB28060	Apoptosis , c-Met/HGFR
	Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.		Apoptosis , c-Met/HGFR
T14511	BAY1082439		Apoptosis , PI3K
	BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms o...		Apoptosis , PI3K
TQ0126	Mirodenafil dihydrochloride	SK-3530 dihydrochloride	PDE
	Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T4260	Capmatinib 2HCl	INC-280 2HCl,INCB28060 2HCl	c-Met/HGFR
	Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-...		c-Met/HGFR
T4310	Prexasertib	LY2606368	Apoptosis , Chk
	Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.		Apoptosis , Chk
T20792	W-7 hydrochloride	W 7 HCl,W7 HCl,W-7 HCl	CaMK , Apoptosis , Myosin , PDE
	W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.		CaMK , Apoptosis , Myosin , PDE
T2287	PIK-75 hydrochloride	PIK-75 HCl,PIK-75	Apoptosis , DNA-PK , PI3K
	PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.		Apoptosis , DNA-PK , PI3K
T15378	Gemcitabine elaidate	Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126	Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
	Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel...		Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
T21017	5'-Amino-5'-deoxyadenosine	5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis , Adenosine Receptor
	5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...		Apoptosis , Adenosine Receptor
T27582	ICRT-5	iCRT 5,iCRT5	Apoptosis , Wnt/beta-catenin
	iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity, blocking Wnt/β-catenin expression and inducing apoptosis. iCRT-5 can be used in the study of multiple myeloma.		Apoptosis , Wnt/beta-catenin
T77763	Wu-5		DUB
	Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.		DUB
T12617	(R)-CR8 trihydrochloride	CR8, (R)-Isomer trihydrochloride	Apoptosis , CDK
	(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1/2/5/7/9 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.		Apoptosis , CDK
T77528	5-LOX-IN-2		Apoptosis , Lipoxygenase
	5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 μM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduce the cell activity of kidney cancer cells and induce apopt...		Apoptosis , Lipoxygenase
T81417	PP5-IN-1		Apoptosis , Phosphatase
	PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.		Apoptosis , Phosphatase
T2383	Panobinostat	NVP-LBH589,LBH589	Apoptosis , HIV Protease , HDAC , Autophagy
	Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity. Panobinostat has antitumor activity and induces apoptosis and autophagy.		Apoptosis , HIV Protease , HDAC , Autophagy
T35407	Ζ-Stat		PKC
	ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]...		PKC
T15239	Epristeride	SKF105657,ONO-9302	Apoptosis , Reductase
	Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Epis...		Apoptosis , Reductase
T6019	Volasertib	BI 6727	Apoptosis , PLK
	Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM).		Apoptosis , PLK

Compounds

5-Fluorouridine

T1349

Synonym:

Target: Others, DNA/RNA Synthesis

5-Fluorouracil

T0984

Synonym: 5-FU,Fluorouracil,NSC 19893,5-Fluoracil

Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, DNA/RNA Synthesis, Endogenous Metabolite

Phenazine methylsulfate

T8138

Synonym: Phenazine methosulfate

Target: Apoptosis, Antibacterial, Antibiotic

TCS PrP Inhibitor 13

T23450

Synonym: 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One

Target: Apoptosis, FLAP

AGK2

T6371

Synonym:

Target: Apoptosis, Sirtuin

G5-7

T8742

Synonym: JAK2 inhibitor G5-7

Target: Apoptosis, JAK

Thioridazine hydrochloride

T0365

Synonym: Mellaril,Aldazine

Target: Apoptosis, Potassium Channel, Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Autophagy

HLY78

T11571

Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Target: Wnt/beta-catenin

VER-50589

T2258

Synonym: VER50589

Target: Apoptosis, HSP

OICR-9429

T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

NSC697923

T6611

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

Floxuridine

T0964

Synonym: 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV

MK-886

T6893

Synonym: MK886,L 663536

Target: Apoptosis, Leukotriene Receptor, COX, PPAR, FLAP

GW 5074

T6525

Synonym: GW5074,Raf1 Kinase Inhibitor I

Target: Apoptosis, Raf

Perphenazine

T1090

Synonym: Perphenazin,Etaperazine,Trilafon

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Olanzapine

T1567

Synonym: LY170053

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR

BAY 61-3606

T4263

Synonym: Syk inhibitor IV

Target: Apoptosis, Syk

BU 224 hydrochloride

T22051

Synonym:

Target: Imidazoline Receptor

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

PU02

T8445

Synonym: PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine

Target: Apoptosis, 5-HT Receptor

GSK4112

T5045

Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Target: Apoptosis, COX, PPAR

DCH36_06

T9373

Synonym: (5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Target: Apoptosis, Epigenetic Reader Domain, Histone Acetyltransferase

D-Pantothenic acid sodium

T3602

Synonym: D-Pantothenate Sodium,D-Pantothenic acid sodium salt,Sodium pantothenate,vitamin B5 sodium

Target: Apoptosis, Others

TCS-PIM-1-4a

T4215

Synonym: SMI-4a

Target: Apoptosis, Pim

(6R)-FR054

T8934

Synonym: FR054

Target: Apoptosis, Others

Fenoprofen calcium hydrate

T6498

Synonym: Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate

Target: Apoptosis, Others, COX

BI 2536

T6173

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, PLK

Capmatinib 2HCl.H2O

T8825

Synonym: INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O

Target: c-Met/HGFR

Capmatinib xHCl

T8416

Synonym: INCB28060,Capmatinib hydrochloride(free base),INC280

Target: c-Met/HGFR

Capmatinib

T1963

Synonym: NVP-INC280,INC-280,INCB28060

Target: Apoptosis, c-Met/HGFR

BAY1082439

T14511

Synonym:

Target: Apoptosis, PI3K

Mirodenafil dihydrochloride

TQ0126

Synonym: SK-3530 dihydrochloride

Target: PDE

Capmatinib 2HCl

T4260

Synonym: INC-280 2HCl,INCB28060 2HCl

Target: Apoptosis, Chk

W-7 hydrochloride

T20792

Synonym: W 7 HCl,W7 HCl,W-7 HCl

Target: CaMK, Apoptosis, Myosin, PDE

PIK-75 hydrochloride

T2287

Synonym: PIK-75 HCl,PIK-75

Target: Apoptosis, DNA-PK, PI3K

Gemcitabine elaidate

T15378

Synonym: Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Autophagy

5'-Amino-5'-deoxyadenosine

T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

iCRT-5

T27582

Synonym: iCRT 5,iCRT5

Target: Apoptosis, Wnt/beta-catenin

(R)-CR8 trihydrochloride

T12617

Synonym: CR8, (R)-Isomer trihydrochloride

Target: Apoptosis, CDK

5-LOX-IN-2

T77528

Synonym:

Target: Apoptosis, Lipoxygenase

PP5-IN-1

T81417

Synonym:

Target: Apoptosis, Phosphatase

Panobinostat

T2383

Synonym: NVP-LBH589,LBH589

Target: Apoptosis, HIV Protease, HDAC, Autophagy

Synonym: SKF105657,ONO-9302

Target: Apoptosis, Reductase

Volasertib

T6019

Synonym: BI 6727

Target: Apoptosis, PLK

Cat No.	Product Name	Synonyms	Targets
T3339	Sophoridine	5-Epidihydrosophocarpine,Dihydro-5-episophocarpine	Apoptosis , Topoisomerase
	Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivatives were synthesized and evaluated for their cytotoxicity ...		Apoptosis , Topoisomerase
TN3110	5-Geranoxy-7-methoxycoumarin		Anti-infection , Antibacterial , Antifungal
	5-Geranoxy-7-methoxycoumarin shows antifungal activity.		Anti-infection , Antibacterial , Antifungal
T3676	Sesamol	1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol	Apoptosis , AMPK
	Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 sig...		Apoptosis , AMPK
T3843	Pinosylvin	3,5-stilbenediol,5-Styrylresorcinol	Apoptosis , Others , Antibacterial , Autophagy
	Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.		Apoptosis , Others , Antibacterial , Autophagy
T8227	5'-Methylthioadenosine	Methylthioadenosine,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine	Endogenous Metabolite
	5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.		Endogenous Metabolite
TN1560	Dehydroeffusol	5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol	MMP , ERK , GPR , Others
	Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reti...		MMP , ERK , GPR , Others
TN1684	Ginsenoside F5		Apoptosis
	Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway		Apoptosis
T1659	Melatonin	Melatonine,N-Acetyl-5-methoxytryptamine	CaMK , Apoptosis , Mitophagy , Estrogen/progestogen Receptor , Melatonin Receptor , Glutathione Peroxidase , Endogenous Metabolite , ROR , Autophagy
	Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin...
T0136	Citicoline	CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline	Apoptosis , Dopamine Receptor , Endogenous Metabolite
	Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.		Apoptosis , Dopamine Receptor , Endogenous Metabolite
T1662	5-Aminolevulinic acid hydrochloride	Hydrangin,5-ALA,5-Aminolevulinic acid HCl,ALA hydrochloride	Apoptosis , Mitophagy , Endogenous Metabolite , Autophagy
	5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.		Apoptosis , Mitophagy , Endogenous Metabolite , Autophagy
TN1465	Cannabigerol		NOS , 5-HT Receptor , ROS
	Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur...		NOS , 5-HT Receptor , ROS
TN1237	3-O-Methylgallic acid	3,4-Dihydroxy-5-methoxybenzoic acid	Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ...		Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
T1508	Decitabine	Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase
	Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis...
T3S0153	Xanthatin		Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T8296	5,7,4'-Trimethoxyflavone	4',5,7-Trimethoxyflavone	Apoptosis , PARP , Caspase
	5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.		Apoptosis , PARP , Caspase
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
T3551	D-Pantothenic acid hemicalcium salt	D-Pantothenic Acid Calcium,Calpanate,Calcium D-pantothenate,Vitamin B5 calcium salt,Calcium pantothenate,Calcium D-Panthotenate	Apoptosis , Endogenous Metabolite
	D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.		Apoptosis , Endogenous Metabolite
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T14121	Actinonin	(-)-Actinonin	Aminopeptidase
	Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin ...		Aminopeptidase
T36179	Aspulvinone O
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulv...

Natural Products

Sophoridine

T3339

Synonym: 5-Epidihydrosophocarpine,Dihydro-5-episophocarpine

Target: Apoptosis, Topoisomerase

5-Geranoxy-7-methoxycoumarin

TN3110

Synonym:

Target: Anti-infection, Antibacterial, Antifungal

Sesamol

T3676

Synonym: 1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol

Target: Apoptosis, AMPK

Pinosylvin

T3843

Synonym: 3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

5'-Methylthioadenosine

T8227

Synonym: Methylthioadenosine,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine

Target: Endogenous Metabolite

Dehydroeffusol

TN1560

Synonym: 5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol

Target: MMP, ERK, GPR, Others

Synonym: Melatonine,N-Acetyl-5-methoxytryptamine

Target: CaMK, Apoptosis, Mitophagy, Estrogen/progestogen Receptor, Melatonin Receptor, Glutathione Peroxidase, Endogenous Metabolite, ROR, Autophagy

Citicoline

T0136

Synonym: CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline

Target: Apoptosis, Dopamine Receptor, Endogenous Metabolite

5-Aminolevulinic acid hydrochloride

T1662

Synonym: Hydrangin,5-ALA,5-Aminolevulinic acid HCl,ALA hydrochloride

Target: Apoptosis, Mitophagy, Endogenous Metabolite, Autophagy

Cannabigerol

TN1465

Synonym:

Target: NOS, 5-HT Receptor, ROS

3-O-Methylgallic acid

TN1237

Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid

Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT

Decitabine

T1508

Synonym: Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

Xanthatin

T3S0153

Synonym:

Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial

5,7,4'-Trimethoxyflavone

T8296

Synonym: 4',5,7-Trimethoxyflavone

Target: Apoptosis, PARP, Caspase

Citicoline sodium

T1208

Synonym: Citicoline sodium salt,CDP-choline

Target: Apoptosis, Others, Endogenous Metabolite

D-Pantothenic acid hemicalcium salt

T3551

Synonym: D-Pantothenic Acid Calcium,Calpanate,Calcium D-pantothenate,Vitamin B5 calcium salt,Calcium pantothenate,Calcium D-Panthotenate

Target: Apoptosis, Endogenous Metabolite

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Stearic acid

T2P2923

Synonym: Isostearic acid,Octadecanoic acid,Cetylacetic acid

Target: Phosphatase, Endogenous Metabolite

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Actinonin

T14121

Synonym: (-)-Actinonin

Target: Aminopeptidase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02519	API5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently supp...
TMPH-00992	BIRC5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	BIRC5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02533	BIRC5 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	BIRC5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is O70201.
TMPH-02532	BIRC5 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	BIRC5 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is O70201.
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPH-02654	FGF-5 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro...
TMPH-01335	FGF-5 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro...
TMPY-00725	COMP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein i...
TMPJ-00854	ETS1 Protein, Human, Recombinant (His)	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...